New high-end microscope for the LMF at the CMCB

The Light Microscopy Facility (LMF) of the CMCB Technology Platform at Technische Universität Dresden (TU Dresden) succeeded with its application for a "New Generation Laser Scanning Confocal Microscope for Multimodal Deep Tissue and Functional Imaging" within the DFG call for large research infrastructure 2018. The DFG call for new experimental research microscopes was well perceived and 50 applications were submitted. Finally 13 projects will be funded.

Hella Hartmann, head of the LMF was in charge of the successful TU Dresden proposal. "Many research groups on the campus are interested in the new technology that the microscope system will supply and supported the application by outstanding scientific contributions. Research groups from the CRTD, the BIOTEC, the B CUBE, the Faculties of Biology and Medicine at TU Dresden, as well as from the Paul Langerhans Institute Dresden contributed research projects and enabled the success of the application", says Hella.

The new instrument - a Leica SP8 DIVE FALCON LIGHTNING system with photomanipulation - will be run within the CMCB Technology Platform and as such be available for all researchers on the campus and beyond. The most innovative technology that it will supply clearly is the fast fluorescence lifetime measurement after single or two photon excitation that can be applied for the measurement of intracellular metabolites and the determination of variety of biophysical parameters within live cells. Installation of the instrument is planned for summer 2019.